Mitochondrial Cardiomyopathy with a Unique ^99mTc-MIBI/¹²³I-BMIPP Mismatch Pattern

Mitochondrial Cardiomyopathy with a Unique 99mTc-MIBI/123I-BMIPP Mismatch Pattern

A 42-year-old man was referred to our hospital due to chest pain, diabetes mellitus, and sensorineural hearing loss. Transthoracic echocardiography revealed diffuse left ventricular hypokinesis. He was diagnosed with mitochondrial disease and a c.A3243G mutation was identified in his mitochondrial DNA. This case of mitochondrial cardiomyopathy demonstrated a low uptake of 123I-BMIPP, while the ...

A case of mitochondrial cardiomyopathy with restrictive transmitral filling pattern

A 61-year-old diabetic woman with a mitochondrial A3243G mutation was hospitalized for evaluation of breathlessness, general fatigue, and leg edema. Chest radiography revealed cardiomegaly with massive pleural effusion. Serum lactate, pyruvate, and brain natriuretic peptide concentrations were elevated. Transthoracic echocardiography revealed a restrictive pattern of transmitral flow, although ...

Midventricular Takotsubo Cardiomyopathy on 99mTc-tetrofosmin and 123I-BMIPP SPECT

Diagnostic utility of 123I-BMIPP imaging in patients with Takotsubo cardiomyopathy.

OBJECTIVE Takotsubo cardiomyopathy is a cardiac syndrome with an acute onset defined by chest symptoms and ST segment elevation on electrocardiograms. Takotsubo cardiomyopathy is sometimes misdiagnosed as acute myocardial infarction (AMI). Therefore a non-invasive diagnostic method is needed to be established for setting up appropriate strategies. The purpose of this study was to detect myocard...

Flow-metabolism mismatch and severe ischemic cardiomyopathy.

A69-year-old man presented to his local physician with progressive dyspnea on exertion and a chest radiograph showing pulmonary edema. He denied any anginal symptoms, but on coronary angiography, he had severe obstructive coronary artery disease involving all 3 major arteries. The left ventricular ejection fraction by multigated angiogram (MUGA) was 22%, with global hypokinesis. A subsequent PE...